Search type: go_term

Results for query: positive regulation of ERK1 and ERK2 cascade

Gene Symbol Gene Name Links to Senescence
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
U: 2
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase
U: 1
AGER advanced glycosylation end product-specific receptor
U: 2
D: 1
AKAP12 A kinase (PRKA) anchor protein (gravin) 12
U: 2
D: 2
ALKAL2 ALK and LTK ligand 2
ALOX15 arachidonate 15-lipoxygenase
U: 1
ANGPT1 angiopoietin 1
U: 3
D: 3
APOE apolipoprotein E
U: 4
D: 1
APP amyloid beta (A4) precursor protein
U: 6
D: 1
ARRB1 arrestin, beta 1
U: 2
D: 1
ARRB2 arrestin, beta 2
D: 1
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
U: 3
ABL2 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
U: 2
ACTA2 actin, alpha 2, smooth muscle, aorta
U: 5
D: 4
ADAM17 a disintegrin and metallopeptidase domain 17
U: 3
D: 2
ATP6V0C ATPase, H+ transporting, lysosomal V0 subunit C
U: 2
BMP2 bone morphogenetic protein 2
U: 6
D: 1
BMP4 bone morphogenetic protein 4
U: 4
D: 1
BMPER BMP-binding endothelial regulator
U: 1
BRAF Braf transforming gene
U: 24
D: 4
C3 complement component 3
U: 7
C5AR1 complement component 5a receptor 1
U: 2
C5AR2 complement component 5a receptor 2
U: 2
CASR calcium-sensing receptor
D: 1
CAVIN3 caveolae associated 3
D: 2
CCL1 chemokine (C-C motif) ligand 1
U: 3
CCL11 chemokine (C-C motif) ligand 11
U: 4
D: 1
CCL13 C-C motif chemokine ligand 13
U: 2
D: 1
CCL17 chemokine (C-C motif) ligand 17
U: 1
D: 1
CCL2 chemokine (C-C motif) ligand 2
U: 39
D: 4
CCL20 chemokine (C-C motif) ligand 20
U: 9
CCL26 chemokine (C-C motif) ligand 26
U: 1
CCL3 chemokine (C-C motif) ligand 3
U: 11
CCL3L3 C-C motif chemokine ligand 3 like 3
U: 1
CCL4 chemokine (C-C motif) ligand 4
U: 5
CCL5 chemokine (C-C motif) ligand 5
U: 13
D: 1
CCL7 chemokine (C-C motif) ligand 7
U: 7
CCL8 chemokine (C-C motif) ligand 8
U: 5
CCN2 cellular communication network factor 2
U: 2
D: 3
CCR1 chemokine (C-C motif) receptor 1
U: 2
CCR7 C-C motif chemokine receptor 7
U: 2
CD36 CD36 molecule
U: 4
CD4 CD4 antigen
D: 1
CD44 CD44 antigen
U: 6
D: 2
CD74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
D: 1
CFLAR CASP8 and FADD-like apoptosis regulator
U: 1
CHI3L1 chitinase 3 like 1
U: 4
CHRNA7 cholinergic receptor, nicotinic, alpha polypeptide 7
U: 2
D: 1
CIB1 calcium and integrin binding 1 (calmyrin)
D: 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
U: 1
D: 1
CSF1R colony stimulating factor 1 receptor
U: 1
D: 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
U: 4
CAMK2D calcium/calmodulin-dependent protein kinase II, delta
D: 1
CCL9 chemokine (C-C motif) ligand 9
U: 1
CYSLTR2 cysteinyl leukotriene receptor 2
D: 1
DDT D-dopachrome tautomerase
U: 1
DRD2 dopamine receptor D2
U: 1
DCC deleted in colorectal carcinoma
U: 2
DUSP15 dual specificity phosphatase-like 15
U: 1
EGFR epidermal growth factor receptor
U: 1
D: 11
ERBB4 erb-b2 receptor tyrosine kinase 4
U: 2
D: 1
EDNRA endothelin receptor type A
D: 5
EGF epidermal growth factor
U: 4
D: 5
ESR1 estrogen receptor 1 (alpha)
U: 2
D: 4
ESR2 estrogen receptor 2 (beta)
U: 2
D: 1
F2R coagulation factor II (thrombin) receptor
U: 2
D: 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
U: 2
D: 1
FBXW7 F-box and WD-40 domain protein 7
U: 1
FFAR4 free fatty acid receptor 4
U: 1
FGF10 fibroblast growth factor 10
D: 1
FGF18 fibroblast growth factor 18
U: 3
FGF2 fibroblast growth factor 2
U: 14
D: 6
FGF4 fibroblast growth factor 4
FGFR2 fibroblast growth factor receptor 2
U: 3
D: 1
FGFR3 fibroblast growth factor receptor 3
U: 3
D: 1
FGFR4 fibroblast growth factor receptor 4
D: 3
FLT4 FMS-like tyrosine kinase 4
U: 1
FGFBP3 fibroblast growth factor binding protein 3
D: 1
GAS6 growth arrest specific 6
U: 3
D: 2
GATA4 GATA binding protein 4
U: 5
GCG glucagon
D: 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
U: 1
GLIPR2 GLI pathogenesis-related 2
U: 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
U: 1
GPBAR1 G protein-coupled bile acid receptor 1
D: 1
GPER1 G protein-coupled estrogen receptor 1
U: 1
D: 1
GPNMB glycoprotein (transmembrane) nmb
U: 5
GPR183 G protein-coupled receptor 183
U: 1
GPR55 G protein-coupled receptor 55
D: 1
HAVCR2 hepatitis A virus cellular receptor 2
U: 3
HCRTR1 hypocretin (orexin) receptor 1
U: 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
U: 2
HMGB1 high mobility group box 1
U: 5
D: 7
HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
U: 2
D: 2
HRAS Harvey rat sarcoma virus oncogene
U: 32
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A
U: 2
ICAM1 intercellular adhesion molecule 1
U: 16
IL1A interleukin 1 alpha
U: 31
D: 6
IL1B interleukin 1 beta
U: 47
D: 9
IL6 interleukin 6
U: 97
D: 19
ITGB3 integrin beta 3
U: 5
D: 1
JUN jun proto-oncogene
U: 3
D: 4
KDR kinase insert domain protein receptor
U: 2
D: 2
KARS lysyl-tRNA synthetase
D: 1
LGALS9 galectin 9
U: 3
D: 1
LRP1 low density lipoprotein receptor-related protein 1
U: 3
MAP2K1 mitogen-activated protein kinase kinase 1
U: 3
MAP2K7 mitogen-activated protein kinase kinase 7
D: 3
MAP3K12 mitogen-activated protein kinase kinase kinase 12
U: 1
MAPK3 mitogen-activated protein kinase 3
U: 10
D: 3
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
U: 1
D: 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
U: 2
D: 5
MIR126 microRNA 126
U: 1
D: 2
MIR21 microRNA 21
U: 2
D: 1
MIR221 microRNA 221
D: 1
MIR222 microRNA 222
U: 1
MIR23A microRNA 23a
U: 4
MIR24-1 microRNA 24-1
U: 1
MIR24-2 microRNA 24-2
MIR27B microRNA 27b
U: 4
MT3 metallothionein 3
U: 2
D: 1
MTURN maturin, neural progenitor differentiation regulator homolog
U: 3
NDRG4 N-myc downstream regulated gene 4
D: 1
NECAB2 N-terminal EF-hand calcium binding protein 2
U: 2
NELFE negative elongation factor complex member E
D: 1
NOD1 nucleotide-binding oligomerization domain containing 1
D: 2
NOD2 nucleotide-binding oligomerization domain containing 2
U: 1
NOTCH1 notch 1
U: 8
D: 2
NOX4 NADPH oxidase 4
U: 18
D: 2
NPNT nephronectin
U: 2
NPTN neuroplastin
U: 2
NQO2 N-ribosyldihydronicotinamide quinone reductase 2
D: 1
NRP1 neuropilin 1
U: 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
U: 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
U: 2
NGF nerve growth factor
U: 3
NRXN1 neurexin I
U: 1
P2RY1 purinergic receptor P2Y, G-protein coupled 1
U: 1
D: 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
D: 1
PDGFA platelet derived growth factor, alpha
U: 3
PDGFB platelet derived growth factor, B polypeptide
U: 3
D: 1
PDGFC platelet-derived growth factor, C polypeptide
U: 3
PDGFD platelet-derived growth factor, D polypeptide
D: 1
PDGFRA platelet derived growth factor receptor, alpha polypeptide
U: 1
D: 2
PDGFRB platelet derived growth factor receptor, beta polypeptide
D: 3
PHB prohibitin
U: 2
D: 2
PHB2 prohibitin 2
D: 1
PLA2G2A phospholipase A2 group IIA
U: 1
PLA2G5 phospholipase A2, group V
U: 1
D: 1
PRKCA protein kinase C, alpha
U: 3
D: 2
PRKCZ protein kinase C, zeta
D: 1
PRKD2 protein kinase D2
U: 1
D: 1
PTEN phosphatase and tensin homolog
U: 6
D: 20
PTK2B PTK2 protein tyrosine kinase 2 beta
U: 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
U: 1
D: 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
D: 1
PTPRC protein tyrosine phosphatase, receptor type, C
U: 2
PYCARD PYD and CARD domain containing
U: 1
RAP1A RAS-related protein 1a
U: 2
RAP1B RAS related protein 1b
D: 1
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
U: 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
D: 1
RIPK2 receptor (TNFRSF)-interacting serine-threonine kinase 2
U: 1
D: 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
U: 1
D: 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
U: 1
D: 1
S100A7 S100 calcium binding protein A7
D: 1
SEMA7A sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
U: 2
D: 1
SERPINF2 serine (or cysteine) peptidase inhibitor, clade F, member 2
U: 2
SHC1 src homology 2 domain-containing transforming protein C1
U: 7
D: 1
SLC30A10 solute carrier family 30, member 10
D: 1
SPRY2 sprouty RTK signaling antagonist 2
D: 3
SRC Rous sarcoma oncogene
U: 2
D: 6
TEK TEK receptor tyrosine kinase
D: 2
TGFB1 transforming growth factor, beta 1
U: 49
D: 4
THPO thrombopoietin
U: 2
D: 1
TLR4 toll-like receptor 4
U: 7
D: 1
TNF tumor necrosis factor
U: 48
D: 7
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
U: 4
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
U: 1
D: 1
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
U: 5
TREM2 triggering receptor expressed on myeloid cells 2
D: 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
U: 1
TLR2 toll-like receptor 2
U: 3
VEGFA vascular endothelial growth factor A
U: 10
D: 5
XCL1 chemokine (C motif) ligand 1
U: 1
D: 1