Search type: go_term
Results for query: positive regulation of ERK1 and ERK2 cascade
| Gene Symbol | Gene Name | Links to Senescence |
|---|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
U: 2
|
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase |
U: 1
|
| AGER | advanced glycosylation end product-specific receptor |
U: 2
D: 1
|
| AKAP12 | A kinase (PRKA) anchor protein (gravin) 12 |
U: 2
D: 2
|
| ALKAL2 | ALK and LTK ligand 2 | |
| ALOX15 | arachidonate 15-lipoxygenase |
U: 1
|
| ANGPT1 | angiopoietin 1 |
U: 3
D: 3
|
| APOE | apolipoprotein E |
U: 4
D: 1
|
| APP | amyloid beta (A4) precursor protein |
U: 6
D: 1
|
| ARRB1 | arrestin, beta 1 |
U: 2
D: 1
|
| ARRB2 | arrestin, beta 2 |
D: 1
|
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 |
U: 3
|
| ABL2 | v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) |
U: 2
|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
U: 5
D: 4
|
| ADAM17 | a disintegrin and metallopeptidase domain 17 |
U: 3
D: 2
|
| ATP6V0C | ATPase, H+ transporting, lysosomal V0 subunit C |
U: 2
|
| BMP2 | bone morphogenetic protein 2 |
U: 6
D: 1
|
| BMP4 | bone morphogenetic protein 4 |
U: 4
D: 1
|
| BMPER | BMP-binding endothelial regulator |
U: 1
|
| BRAF | Braf transforming gene |
U: 24
D: 4
|
| C3 | complement component 3 |
U: 7
|
| C5AR1 | complement component 5a receptor 1 |
U: 2
|
| C5AR2 | complement component 5a receptor 2 |
U: 2
|
| CASR | calcium-sensing receptor |
D: 1
|
| CAVIN3 | caveolae associated 3 |
D: 2
|
| CCL1 | chemokine (C-C motif) ligand 1 |
U: 3
|
| CCL11 | chemokine (C-C motif) ligand 11 |
U: 4
D: 1
|
| CCL13 | C-C motif chemokine ligand 13 |
U: 2
D: 1
|
| CCL17 | chemokine (C-C motif) ligand 17 |
U: 1
D: 1
|
| CCL2 | chemokine (C-C motif) ligand 2 |
U: 39
D: 4
|
| CCL20 | chemokine (C-C motif) ligand 20 |
U: 9
|
| CCL26 | chemokine (C-C motif) ligand 26 |
U: 1
|
| CCL3 | chemokine (C-C motif) ligand 3 |
U: 11
|
| CCL3L3 | C-C motif chemokine ligand 3 like 3 |
U: 1
|
| CCL4 | chemokine (C-C motif) ligand 4 |
U: 5
|
| CCL5 | chemokine (C-C motif) ligand 5 |
U: 13
D: 1
|
| CCL7 | chemokine (C-C motif) ligand 7 |
U: 7
|
| CCL8 | chemokine (C-C motif) ligand 8 |
U: 5
|
| CCN2 | cellular communication network factor 2 |
U: 2
D: 3
|
| CCR1 | chemokine (C-C motif) receptor 1 |
U: 2
|
| CCR7 | C-C motif chemokine receptor 7 |
U: 2
|
| CD36 | CD36 molecule |
U: 4
|
| CD4 | CD4 antigen |
D: 1
|
| CD44 | CD44 antigen |
U: 6
D: 2
|
| CD74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
D: 1
|
| CFLAR | CASP8 and FADD-like apoptosis regulator |
U: 1
|
| CHI3L1 | chitinase 3 like 1 |
U: 4
|
| CHRNA7 | cholinergic receptor, nicotinic, alpha polypeptide 7 |
U: 2
D: 1
|
| CIB1 | calcium and integrin binding 1 (calmyrin) |
D: 1
|
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
U: 1
D: 1
|
| CSF1R | colony stimulating factor 1 receptor |
U: 1
D: 1
|
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
U: 4
|
| CAMK2D | calcium/calmodulin-dependent protein kinase II, delta |
D: 1
|
| CCL9 | chemokine (C-C motif) ligand 9 |
U: 1
|
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
D: 1
|
| DDT | D-dopachrome tautomerase |
U: 1
|
| DRD2 | dopamine receptor D2 |
U: 1
|
| DCC | deleted in colorectal carcinoma |
U: 2
|
| DUSP15 | dual specificity phosphatase-like 15 |
U: 1
|
| EGFR | epidermal growth factor receptor |
U: 1
D: 11
|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
U: 2
D: 1
|
| EDNRA | endothelin receptor type A |
D: 5
|
| EGF | epidermal growth factor |
U: 4
D: 5
|
| ESR1 | estrogen receptor 1 (alpha) |
U: 2
D: 4
|
| ESR2 | estrogen receptor 2 (beta) |
U: 2
D: 1
|
| F2R | coagulation factor II (thrombin) receptor |
U: 2
D: 1
|
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
U: 2
D: 1
|
| FBXW7 | F-box and WD-40 domain protein 7 |
U: 1
|
| FFAR4 | free fatty acid receptor 4 |
U: 1
|
| FGF10 | fibroblast growth factor 10 |
D: 1
|
| FGF18 | fibroblast growth factor 18 |
U: 3
|
| FGF2 | fibroblast growth factor 2 |
U: 14
D: 6
|
| FGF4 | fibroblast growth factor 4 | |
| FGFR2 | fibroblast growth factor receptor 2 |
U: 3
D: 1
|
| FGFR3 | fibroblast growth factor receptor 3 |
U: 3
D: 1
|
| FGFR4 | fibroblast growth factor receptor 4 |
D: 3
|
| FLT4 | FMS-like tyrosine kinase 4 |
U: 1
|
| FGFBP3 | fibroblast growth factor binding protein 3 |
D: 1
|
| GAS6 | growth arrest specific 6 |
U: 3
D: 2
|
| GATA4 | GATA binding protein 4 |
U: 5
|
| GCG | glucagon |
D: 1
|
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme |
U: 1
|
| GLIPR2 | GLI pathogenesis-related 2 |
U: 1
|
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 |
U: 1
|
| GPBAR1 | G protein-coupled bile acid receptor 1 |
D: 1
|
| GPER1 | G protein-coupled estrogen receptor 1 |
U: 1
D: 1
|
| GPNMB | glycoprotein (transmembrane) nmb |
U: 5
|
| GPR183 | G protein-coupled receptor 183 |
U: 1
|
| GPR55 | G protein-coupled receptor 55 |
D: 1
|
| HAVCR2 | hepatitis A virus cellular receptor 2 |
U: 3
|
| HCRTR1 | hypocretin (orexin) receptor 1 |
U: 1
|
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
U: 2
|
| HMGB1 | high mobility group box 1 |
U: 5
D: 7
|
| HMGCR | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
U: 2
D: 2
|
| HRAS | Harvey rat sarcoma virus oncogene |
U: 32
|
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A |
U: 2
|
| ICAM1 | intercellular adhesion molecule 1 |
U: 16
|
| IL1A | interleukin 1 alpha |
U: 31
D: 6
|
| IL1B | interleukin 1 beta |
U: 47
D: 9
|
| IL6 | interleukin 6 |
U: 97
D: 19
|
| ITGB3 | integrin beta 3 |
U: 5
D: 1
|
| JUN | jun proto-oncogene |
U: 3
D: 4
|
| KDR | kinase insert domain protein receptor |
U: 2
D: 2
|
| KARS | lysyl-tRNA synthetase |
D: 1
|
| LGALS9 | galectin 9 |
U: 3
D: 1
|
| LRP1 | low density lipoprotein receptor-related protein 1 |
U: 3
|
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
U: 3
|
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
D: 3
|
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
U: 1
|
| MAPK3 | mitogen-activated protein kinase 3 |
U: 10
D: 3
|
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
U: 1
D: 2
|
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
U: 2
D: 5
|
| MIR126 | microRNA 126 |
U: 1
D: 2
|
| MIR21 | microRNA 21 |
U: 2
D: 1
|
| MIR221 | microRNA 221 |
D: 1
|
| MIR222 | microRNA 222 |
U: 1
|
| MIR23A | microRNA 23a |
U: 4
|
| MIR24-1 | microRNA 24-1 |
U: 1
|
| MIR24-2 | microRNA 24-2 | |
| MIR27B | microRNA 27b |
U: 4
|
| MT3 | metallothionein 3 |
U: 2
D: 1
|
| MTURN | maturin, neural progenitor differentiation regulator homolog |
U: 3
|
| NDRG4 | N-myc downstream regulated gene 4 |
D: 1
|
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
U: 2
|
| NELFE | negative elongation factor complex member E |
D: 1
|
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
D: 2
|
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
U: 1
|
| NOTCH1 | notch 1 |
U: 8
D: 2
|
| NOX4 | NADPH oxidase 4 |
U: 18
D: 2
|
| NPNT | nephronectin |
U: 2
|
| NPTN | neuroplastin |
U: 2
|
| NQO2 | N-ribosyldihydronicotinamide quinone reductase 2 |
D: 1
|
| NRP1 | neuropilin 1 |
U: 2
|
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
U: 2
|
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
U: 2
|
| NGF | nerve growth factor |
U: 3
|
| NRXN1 | neurexin I |
U: 1
|
| P2RY1 | purinergic receptor P2Y, G-protein coupled 1 |
U: 1
D: 1
|
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
D: 1
|
| PDGFA | platelet derived growth factor, alpha |
U: 3
|
| PDGFB | platelet derived growth factor, B polypeptide |
U: 3
D: 1
|
| PDGFC | platelet-derived growth factor, C polypeptide |
U: 3
|
| PDGFD | platelet-derived growth factor, D polypeptide |
D: 1
|
| PDGFRA | platelet derived growth factor receptor, alpha polypeptide |
U: 1
D: 2
|
| PDGFRB | platelet derived growth factor receptor, beta polypeptide |
D: 3
|
| PHB | prohibitin |
U: 2
D: 2
|
| PHB2 | prohibitin 2 |
D: 1
|
| PLA2G2A | phospholipase A2 group IIA |
U: 1
|
| PLA2G5 | phospholipase A2, group V |
U: 1
D: 1
|
| PRKCA | protein kinase C, alpha |
U: 3
D: 2
|
| PRKCZ | protein kinase C, zeta |
D: 1
|
| PRKD2 | protein kinase D2 |
U: 1
D: 1
|
| PTEN | phosphatase and tensin homolog |
U: 6
D: 20
|
| PTK2B | PTK2 protein tyrosine kinase 2 beta |
U: 1
|
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
U: 1
D: 2
|
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
D: 1
|
| PTPRC | protein tyrosine phosphatase, receptor type, C |
U: 2
|
| PYCARD | PYD and CARD domain containing |
U: 1
|
| RAP1A | RAS-related protein 1a |
U: 2
|
| RAP1B | RAS related protein 1b |
D: 1
|
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
U: 1
|
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
D: 1
|
| RIPK2 | receptor (TNFRSF)-interacting serine-threonine kinase 2 |
U: 1
D: 1
|
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
U: 1
D: 1
|
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
U: 1
D: 1
|
| S100A7 | S100 calcium binding protein A7 |
D: 1
|
| SEMA7A | sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A |
U: 2
D: 1
|
| SERPINF2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 |
U: 2
|
| SHC1 | src homology 2 domain-containing transforming protein C1 |
U: 7
D: 1
|
| SLC30A10 | solute carrier family 30, member 10 |
D: 1
|
| SPRY2 | sprouty RTK signaling antagonist 2 |
D: 3
|
| SRC | Rous sarcoma oncogene |
U: 2
D: 6
|
| TEK | TEK receptor tyrosine kinase |
D: 2
|
| TGFB1 | transforming growth factor, beta 1 |
U: 49
D: 4
|
| THPO | thrombopoietin |
U: 2
D: 1
|
| TLR4 | toll-like receptor 4 |
U: 7
D: 1
|
| TNF | tumor necrosis factor |
U: 48
D: 7
|
| TNFAIP8L3 | tumor necrosis factor, alpha-induced protein 8-like 3 |
U: 4
|
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
U: 1
D: 1
|
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
U: 5
|
| TREM2 | triggering receptor expressed on myeloid cells 2 |
D: 1
|
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
U: 1
|
| TLR2 | toll-like receptor 2 |
U: 3
|
| VEGFA | vascular endothelial growth factor A |
U: 10
D: 5
|
| XCL1 | chemokine (C motif) ligand 1 |
U: 1
D: 1
|