Search type: go_term
Results for query: cytokine-mediated signaling pathway
| Gene Symbol | Gene Name | Links to Senescence |
|---|---|---|
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 |
U: 1
|
| AKT1 | AKT serine/threonine kinase 1 |
U: 21
D: 24
|
| ALOX15 | arachidonate 15-lipoxygenase |
U: 1
|
| ALOX5 | arachidonate 5-lipoxygenase |
U: 2
|
| ANXA1 | annexin A1 |
U: 2
|
| AXL | AXL receptor tyrosine kinase |
U: 1
D: 4
|
| BCL2 | BCL2 apoptosis regulator |
U: 11
D: 5
|
| BCL2L1 | BCL2 like 1 |
U: 11
D: 6
|
| BCL6 | BCL6 transcription repressor |
U: 3
D: 1
|
| BIRC5 | baculoviral IAP repeat containing 5 |
U: 3
D: 14
|
| CASP1 | caspase 1 |
U: 2
D: 3
|
| CASP3 | caspase 3 |
U: 3
D: 5
|
| CAV1 | caveolin 1, caveolae protein |
U: 15
D: 5
|
| CBL | Cbl proto-oncogene |
U: 1
D: 1
|
| CCL11 | C-C motif chemokine ligand 11 |
U: 4
D: 1
|
| CCL2 | chemokine (C-C motif) ligand 2 |
U: 39
D: 4
|
| CCL20 | C-C motif chemokine ligand 20 |
U: 9
|
| CCL3 | C-C motif chemokine ligand 3 |
U: 11
|
| CCL3L3 | C-C motif chemokine ligand 3 like 3 |
U: 1
|
| CCL4 | C-C motif chemokine ligand 4 |
U: 5
|
| CCL5 | C-C motif chemokine ligand 5 |
U: 13
D: 1
|
| CCND1 | cyclin D1 |
U: 17
D: 8
|
| CCR1 | C-C motif chemokine receptor 1 |
U: 2
|
| CD24 | CD24 molecule |
U: 2
|
| CD36 | CD36 molecule |
U: 4
|
| CD4 | CD4 molecule |
D: 1
|
| CD74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
D: 1
|
| CD86 | CD86 molecule |
U: 1
|
| CDKN1A | cyclin dependent kinase inhibitor 1A |
U: 208
D: 24
|
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
U: 4
|
| CEBPD | CCAAT enhancer binding protein delta |
U: 2
D: 1
|
| CLCF1 | cardiotrophin like cytokine factor 1 |
U: 1
|
| CNOT9 | CCR4-NOT transcription complex, subunit 9 | |
| CNTFR | ciliary neurotrophic factor receptor |
U: 1
D: 1
|
| COL1A2 | collagen type I alpha 2 chain |
U: 3
|
| CRKL | CRK like proto-oncogene, adaptor protein |
U: 1
D: 1
|
| CRLF1 | cytokine receptor-like factor 1 |
U: 3
D: 1
|
| CSF1 | colony stimulating factor 1 |
U: 5
|
| CSF1R | colony stimulating factor 1 receptor |
U: 1
D: 1
|
| CSF2 | colony stimulating factor 2 |
U: 11
D: 2
|
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
U: 1
D: 1
|
| CSF3 | colony stimulating factor 3 |
U: 7
D: 1
|
| CTF1 | cardiotrophin 1 |
U: 1
|
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
U: 4
|
| CXCL1 | C-X-C motif chemokine ligand 1 |
U: 27
D: 6
|
| CXCL10 | C-X-C motif chemokine ligand 10 |
U: 11
|
| CXCL2 | C-X-C motif chemokine ligand 2 |
U: 16
D: 3
|
| CXCL8 | C-X-C motif chemokine ligand 8 |
U: 49
D: 10
|
| DUOX1 | dual oxidase 1 |
U: 2
|
| DUOX2 | dual oxidase 2 |
U: 1
|
| EBI3 | Epstein-Barr virus induced gene 3 |
U: 4
|
| ECM1 | extracellular matrix protein 1 |
U: 4
|
| EDN2 | endothelin 2 |
U: 2
|
| ELF1 | E74 like ETS transcription factor 1 |
U: 2
D: 1
|
| EREG | epiregulin |
U: 3
D: 3
|
| F3 | coagulation factor III, tissue factor |
U: 2
D: 1
|
| FASLG | Fas ligand |
U: 3
|
| FER | fer (fms/fps related) protein kinase |
D: 2
|
| FGF2 | fibroblast growth factor 2 |
U: 14
D: 6
|
| FLT3LG | fms related receptor tyrosine kinase 3 ligand |
U: 2
|
| FN1 | fibronectin 1 |
U: 7
D: 3
|
| FOS | Fos proto-oncogene, AP-1 transcription factor subunit |
U: 3
D: 6
|
| FOXO1 | forkhead box O1 |
U: 10
D: 3
|
| FOXO3 | forkhead box O3 |
U: 6
D: 10
|
| FPR1 | formyl peptide receptor 1 |
U: 1
|
| FSCN1 | fascin actin-bundling protein 1 |
U: 1
D: 2
|
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
D: 2
|
| FZD4 | frizzled class receptor 4 |
D: 2
|
| FKBP1A | FK506 binding protein 1a |
U: 1
|
| GAB2 | GRB2 associated binding protein 2 |
D: 1
|
| GAS6 | growth arrest specific 6 |
U: 3
D: 2
|
| GATA3 | GATA binding protein 3 |
U: 1
|
| GHR | growth hormone receptor |
U: 3
|
| GREM2 | gremlin 2, DAN family BMP antagonist |
D: 1
|
| HGF | hepatocyte growth factor |
U: 4
D: 1
|
| HIF1A | hypoxia inducible factor 1 subunit alpha |
U: 4
D: 8
|
| HMOX1 | heme oxygenase 1 |
U: 5
D: 6
|
| HSP90AA1 | heat shock protein 90 alpha family class A member 1 |
U: 2
D: 4
|
| HSP90B1 | heat shock protein 90 beta family member 1 |
U: 2
D: 1
|
| HSPA8 | heat shock protein family A (Hsp70) member 8 |
U: 2
|
| ICAM1 | intercellular adhesion molecule 1 |
U: 16
|
| IFNA1 | interferon alpha 1 |
U: 1
|
| IFNAR1 | interferon (alpha and beta) receptor 1 |
D: 1
|
| IFNAR2 | interferon (alpha and beta) receptor 2 |
U: 1
D: 1
|
| IFNB1 | interferon beta 1, fibroblast |
U: 2
|
| IFNE | interferon epsilon |
U: 2
D: 1
|
| IFNGR1 | interferon gamma receptor 1 |
U: 3
D: 2
|
| IFNGR2 | interferon gamma receptor 2 |
U: 3
D: 1
|
| IFNLR1 | interferon lambda receptor 1 |
U: 1
|
| IL10 | interleukin 10 |
U: 4
D: 3
|
| IL11 | interleukin 11 |
U: 3
D: 4
|
| IL11RA | interleukin 11 receptor subunit alpha |
U: 2
D: 2
|
| IL12A | interleukin 12A |
U: 5
|
| IL12RB2 | interleukin 12 receptor, beta 2 |
U: 1
|
| IL13 | interleukin 13 |
U: 3
|
| IL13RA1 | interleukin 13 receptor, alpha 1 |
U: 1
D: 1
|
| IL13RA2 | interleukin 13 receptor, alpha 2 |
D: 1
|
| IL16 | interleukin 16 |
U: 1
D: 3
|
| IL18 | interleukin 18 |
U: 8
D: 1
|
| IL1A | interleukin 1 alpha |
U: 31
D: 6
|
| IL1B | interleukin 1 beta |
U: 47
D: 9
|
| IL1R1 | interleukin 1 receptor, type I |
U: 1
D: 1
|
| IL1R2 | interleukin 1 receptor type 2 |
U: 1
D: 1
|
| IL1RAP | interleukin 1 receptor accessory protein |
U: 3
D: 2
|
| IL1RN | interleukin 1 receptor antagonist |
U: 4
D: 1
|
| IL2 | interleukin 2 |
U: 3
D: 1
|
| IL20 | interleukin 20 |
U: 1
|
| IL20RB | interleukin 20 receptor beta |
U: 1
|
| IL22 | interleukin 22 |
U: 2
D: 1
|
| IL22RA1 | interleukin 22 receptor, alpha 1 |
U: 1
|
| IL23A | interleukin 23 subunit alpha |
U: 5
D: 1
|
| IL23R | interleukin 23 receptor |
U: 1
|
| IL24 | interleukin 24 |
U: 2
|
| IL27RA | interleukin 27 receptor, alpha |
U: 2
D: 1
|
| IL2RB | interleukin 2 receptor, beta chain |
U: 1
|
| IL3 | interleukin 3 |
U: 1
|
| IL31RA | interleukin 31 receptor A |
U: 1
D: 1
|
| IL32 | interleukin 32 |
U: 3
|
| IL34 | interleukin 34 |
U: 1
D: 1
|
| IL36B | interleukin 36 beta |
U: 1
|
| IL36RN | interleukin 36 receptor antagonist |
U: 2
|
| IL4 | interleukin 4 |
U: 4
|
| IL4R | interleukin 4 receptor |
U: 2
D: 2
|
| IL5 | interleukin 5 |
U: 1
|
| IL6 | interleukin 6 |
U: 97
D: 19
|
| IL6R | interleukin 6 receptor |
U: 2
D: 1
|
| IL6ST | interleukin 6 signal transducer |
U: 2
D: 1
|
| IL7 | interleukin 7 |
U: 5
|
| INPP5D | inositol polyphosphate-5-phosphatase D |
U: 2
|
| INPPL1 | inositol polyphosphate phosphatase like 1 |
U: 3
|
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
U: 2
D: 3
|
| IRAK2 | interleukin-1 receptor-associated kinase 2 |
U: 2
D: 2
|
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
U: 1
|
| IRF4 | interferon regulatory factor 4 | |
| ITGAM | integrin subunit alpha M |
U: 1
|
| ITGAX | integrin subunit alpha X |
U: 2
|
| ITGB1 | integrin subunit beta 1 |
U: 3
D: 1
|
| IRF5 | interferon regulatory factor 5 |
U: 4
D: 1
|
| JAK1 | Janus kinase 1 |
U: 3
|
| JAK2 | Janus kinase 2 |
U: 3
|
| JAK3 | Janus kinase 3 |
U: 2
|
| JUNB | JunB proto-oncogene, AP-1 transcription factor subunit |
U: 5
D: 1
|
| KIT | KIT proto-oncogene receptor tyrosine kinase |
U: 1
D: 2
|
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
U: 18
D: 3
|
| KLF6 | Kruppel-like factor 6 |
U: 2
D: 1
|
| LAMA5 | laminin subunit alpha 5 |
U: 6
D: 1
|
| LCN2 | lipocalin 2 |
U: 2
D: 1
|
| LEPR | leptin receptor |
U: 3
D: 1
|
| LIF | LIF interleukin 6 family cytokine |
U: 6
D: 3
|
| LIFR | LIF receptor alpha |
D: 2
|
| LRP8 | LDL receptor related protein 8 |
D: 2
|
| MAOA | monoamine oxidase A |
U: 4
D: 1
|
| MCL1 | MCL1 apoptosis regulator, BCL2 family member |
U: 3
D: 2
|
| MIR125A | microRNA 125a |
U: 1
|
| MIR21 | microRNA 21 |
U: 2
D: 1
|
| MIR29B1 | microRNA 29b-1 |
U: 2
|
| MMP1 | matrix metallopeptidase 1 |
U: 11
D: 5
|
| MMP2 | matrix metallopeptidase 2 |
U: 11
D: 1
|
| MMP3 | matrix metallopeptidase 3 |
U: 22
D: 2
|
| MMP9 | matrix metallopeptidase 9 |
U: 14
D: 3
|
| MUC1 | mucin 1, cell surface associated |
U: 4
D: 1
|
| MYC | MYC proto-oncogene, bHLH transcription factor |
U: 7
D: 24
|
| MYD88 | myeloid differentiation primary response gene 88 |
U: 1
|
| NANOG | Nanog homeobox |
U: 1
D: 6
|
| NDN | necdin, MAGE family member |
U: 1
D: 1
|
| NOS2 | nitric oxide synthase 2 |
U: 7
D: 2
|
| NUP85 | nucleoporin 85 |
U: 2
D: 1
|
| OSM | oncostatin M |
U: 1
|
| OSMR | oncostatin M receptor |
U: 1
D: 1
|
| PAFAH1B1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 |
U: 1
|
| PALM3 | paralemmin 3 |
D: 1
|
| PF4 | platelet factor 4 |
U: 3
D: 1
|
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
U: 5
D: 5
|
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
U: 2
|
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
U: 2
D: 1
|
| PIK3R1 | phosphoinositide-3-kinase regulatory subunit 1 |
U: 1
|
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
U: 7
D: 2
|
| POMC | proopiomelanocortin |
U: 1
|
| POU2F1 | POU class 2 homeobox 1 |
U: 2
D: 1
|
| PRKACA | protein kinase cAMP-activated catalytic subunit alpha |
U: 1
|
| PRLR | prolactin receptor |
U: 1
|
| PTGS2 | prostaglandin-endoperoxide synthase 2 |
U: 12
D: 4
|
| PTPN11 | protein tyrosine phosphatase non-receptor type 11 |
U: 1
D: 2
|
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
D: 1
|
| PTPRC | protein tyrosine phosphatase, receptor type, C |
U: 2
|
| PTPRN | protein tyrosine phosphatase, receptor type, N |
U: 1
|
| PTPRZ1 | protein tyrosine phosphatase receptor type Z1 |
U: 3
D: 2
|
| PXDN | peroxidasin |
U: 4
|
| PTPRF | protein tyrosine phosphatase, receptor type, F |
U: 1
|
| RAPGEF1 | Rap guanine nucleotide exchange factor 1 |
U: 1
|
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
U: 12
D: 5
|
| RHOU | ras homolog family member U |
U: 3
|
| RIPK2 | receptor (TNFRSF)-interacting serine-threonine kinase 2 |
U: 1
D: 1
|
| RORA | RAR related orphan receptor A |
U: 5
|
| RPS27A | ribosomal protein S27a |
U: 1
|
| RUNX1 | RUNX family transcription factor 1 |
U: 4
|
| S1PR1 | sphingosine-1-phosphate receptor 1 |
D: 2
|
| SAA1 | serum amyloid A1 |
U: 5
|
| SDC1 | syndecan 1 |
U: 5
D: 1
|
| SHC1 | SHC adaptor protein 1 |
U: 7
D: 1
|
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
U: 1
D: 1
|
| SOCS1 | suppressor of cytokine signaling 1 |
U: 4
|
| SOCS3 | suppressor of cytokine signaling 3 |
U: 1
D: 2
|
| SOX2 | SRY-box transcription factor 2 |
U: 3
D: 10
|
| STAT1 | signal transducer and activator of transcription 1 |
U: 12
D: 1
|
| STAT2 | signal transducer and activator of transcription 2 |
U: 2
|
| STAT3 | signal transducer and activator of transcription 3 |
U: 18
D: 6
|
| STAT4 | signal transducer and activator of transcription 4 |
U: 1
|
| STAT5A | signal transducer and activator of transcription 5A |
U: 6
D: 2
|
| STAT5B | signal transducer and activator of transcription 5B |
U: 4
|
| STAT6 | signal transducer and activator of transcription 6 |
U: 4
|
| STX1A | syntaxin 1A |
U: 1
|
| STX3 | syntaxin 3 |
U: 1
|
| STX4 | syntaxin 4 |
U: 4
|
| SH2B2 | SH2B adaptor protein 2 |
U: 1
D: 1
|
| TGFB1 | transforming growth factor beta 1 |
U: 49
D: 4
|
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
U: 9
D: 2
|
| TNF | tumor necrosis factor |
U: 48
D: 7
|
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1a |
U: 4
D: 1
|
| TNFRSF1B | TNF receptor superfamily member 1B |
U: 3
D: 2
|
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
U: 5
|
| TP53 | tumor protein p53 |
U: 243
D: 9
|
| TRIM44 | tripartite motif-containing 44 |
D: 1
|
| TSLP | thymic stromal lymphopoietin |
U: 1
D: 1
|
| TWIST1 | twist family bHLH transcription factor 1 |
D: 13
|
| TXLNA | taxilin alpha |
U: 1
D: 1
|
| TYK2 | tyrosine kinase 2 |
U: 1
|
| TRAF6 | TNF receptor-associated factor 6 |
U: 1
D: 3
|
| UBB | ubiquitin B |
U: 1
|
| UBC | ubiquitin C |
D: 1
|
| VCAM1 | vascular cell adhesion molecule 1 |
U: 4
D: 3
|
| VEGFA | vascular endothelial growth factor A |
U: 10
D: 5
|
| VIM | vimentin |
U: 4
D: 1
|
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
U: 1
D: 2
|
| ZC3H15 | zinc finger CCCH-type containing 15 |
D: 1
|
| ZEB1 | zinc finger E-box binding homeobox 1 |
D: 4
|
| ZNF675 | zinc finger protein 675 |
D: 1
|