HELQ

helicase, POLQ like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA25 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
double-strand break repair via homologous recombination [GO:0000724],
rRNA processing [GO:0006364],
DNA duplex unwinding [GO:0032508],
DNA metabolic process [GO:0006259],
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
DNA binding [GO:0003677],
DNA helicase activity [GO:0003678],
protein binding [GO:0005515],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
nucleic acid binding [GO:0003676],
helicase activity [GO:0004386],
hydrolase activity [GO:0016787],
single-stranded DNA-dependent ATP-dependent DNA helicase activity [GO:0017116],

Cellular Component:
nucleus [GO:0005634],
single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117],