ankyrin repeat domain 27

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
protein transport [GO:0015031],
negative regulation of SNARE complex assembly [GO:0035544],
endosome to melanosome transport [GO:0035646],
positive regulation of GTPase activity [GO:0043547],
early endosome to late endosome transport [GO:0045022],
neuron projection morphogenesis [GO:0048812],
positive regulation of dendrite morphogenesis [GO:0050775],
retrograde transport, endosome to plasma membrane [GO:1990126],
positive regulation of neuron projection development [GO:0010976],

Molecular Function:
SNARE binding [GO:0000149],
guanyl-nucleotide exchange factor activity [GO:0005085],
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rab GTPase binding [GO:0017137],

Cellular Component:
lysosome [GO:0005764],
early endosome [GO:0005769],
late endosome [GO:0005770],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
transport vesicle [GO:0030133],
cytoplasmic vesicle membrane [GO:0030659],
melanosome [GO:0042470],
neuron projection [GO:0043005],
tubular endosome [GO:0097422],
endosome [GO:0005768],
cytoplasmic vesicle [GO:0031410],