GSS

glutathione synthetase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
cellular amino acid metabolic process [GO:0006520],
glutathione biosynthetic process [GO:0006750],
response to oxidative stress [GO:0006979],
nervous system development [GO:0007399],
aging [GO:0007568],
response to xenobiotic stimulus [GO:0009410],
response to nutrient levels [GO:0031667],
response to tumor necrosis factor [GO:0034612],
response to amino acid [GO:0043200],
response to cadmium ion [GO:0046686],

Molecular Function:
magnesium ion binding [GO:0000287],
glutathione synthase activity [GO:0004363],
protein binding [GO:0005515],
ATP binding [GO:0005524],
glycine binding [GO:0016594],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
glutathione binding [GO:0043295],
nucleotide binding [GO:0000166],
ligase activity [GO:0016874],
peptide binding [GO:0042277],
metal ion binding [GO:0046872],

Cellular Component:
cytosol [GO:0005829],
extracellular exosome [GO:0070062],