ANKLE1
ankyrin repeat and LEM domain containing 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
31945125 | Primary astrocytes derived from brain | Human | YES |
GO terms:
Biological Process:
DNA repair [GO:0006281],
protein export from nucleus [GO:0006611],
nucleic acid phosphodiester bond hydrolysis [GO:0090305],
positive regulation of response to DNA damage stimulus [GO:2001022],
cellular response to DNA damage stimulus [GO:0006974],
determination of adult lifespan [GO:0008340],
regulation of T cell differentiation in thymus [GO:0033081],
erythrocyte maturation [GO:0043249],
regulation of B cell differentiation [GO:0045577],
negative regulation of mitotic recombination [GO:0045950],
regulation of alpha-beta T cell differentiation [GO:0046637],
regulation of myeloid progenitor cell differentiation [GO:1905453],
regulation of lymphoid progenitor cell differentiation [GO:1905456],
regulation of response to DNA damage stimulus [GO:2001020],
Molecular Function:
endonuclease activity [GO:0004519],
protein binding [GO:0005515],
nuclease activity [GO:0004518],
hydrolase activity [GO:0016787],
Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],