ankyrin repeat and IBR domain containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
protein polyubiquitination [GO:0000209],
ubiquitin-dependent protein catabolic process [GO:0006511],
positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436],

Molecular Function:
protein binding [GO:0005515],
ubiquitin conjugating enzyme binding [GO:0031624],
metal ion binding [GO:0046872],
ubiquitin protein ligase activity [GO:0061630],
ubiquitin-protein transferase activity [GO:0004842],
transferase activity [GO:0016740],

Cellular Component:
ubiquitin ligase complex [GO:0000151],
cytoplasm [GO:0005737],