ankyrin repeat and FYVE domain containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
endosomal transport [GO:0016197],
endosomal vesicle fusion [GO:0034058],
retrograde transport, endosome to Golgi [GO:0042147],
positive regulation of pinocytosis [GO:0048549],
Golgi to lysosome transport [GO:0090160],

Molecular Function:
Rab GTPase binding [GO:0017137],
metal ion binding [GO:0046872],
phosphatidylinositol phosphate binding [GO:1901981],
protein binding [GO:0005515],

Cellular Component:
cytoplasm [GO:0005737],
endosome [GO:0005768],
early endosome [GO:0005769],
endosome membrane [GO:0010008],
membrane [GO:0016020],
retromer complex [GO:0030904],
cytoplasmic vesicle [GO:0031410],
intracellular membrane-bounded organelle [GO:0043231],
macropinosome [GO:0044354],
lysosomal membrane [GO:0005765],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],