ankyrin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
exocytosis [GO:0006887],
ER to Golgi vesicle-mediated transport [GO:0006888],
cytoskeleton organization [GO:0007010],
signal transduction [GO:0007165],
positive regulation of organelle organization [GO:0010638],
maintenance of epithelial cell apical/basal polarity [GO:0045199],
protein localization to plasma membrane [GO:0072659],
porphyrin-containing compound biosynthetic process [GO:0006779],
monovalent inorganic cation transport [GO:0015672],
erythrocyte development [GO:0048821],
iron ion homeostasis [GO:0055072],

Molecular Function:
structural molecule activity [GO:0005198],
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
cytoskeletal adaptor activity [GO:0008093],
enzyme binding [GO:0019899],
protein phosphatase binding [GO:0019903],
spectrin binding [GO:0030507],
ion channel binding [GO:0044325],
ATPase binding [GO:0051117],

Cellular Component:
nucleus [GO:0005634],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
cytoplasmic side of plasma membrane [GO:0009898],
spectrin-associated cytoskeleton [GO:0014731],
basolateral plasma membrane [GO:0016323],
sarcoplasmic reticulum [GO:0016529],
Z disc [GO:0030018],
axolemma [GO:0030673],
M band [GO:0031430],
sarcolemma [GO:0042383],
neuron projection [GO:0043005],
postsynaptic membrane [GO:0045211],
cytoplasm [GO:0005737],
membrane [GO:0016020],
cortical cytoskeleton [GO:0030863],
A band [GO:0031672],