GPHN

gephyrin

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
Mo-molybdopterin cofactor biosynthetic process [GO:0006777],
establishment of synaptic specificity at neuromuscular junction [GO:0007529],
response to metal ion [GO:0010038],
molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315],
molybdopterin cofactor biosynthetic process [GO:0032324],
oxidation-reduction process [GO:0055114],
glycine receptor clustering [GO:0072579],
gamma-aminobutyric acid receptor clustering [GO:0097112],
postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970],
metabolic process [GO:0008152],
establishment of protein localization [GO:0045184],
neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645],

Molecular Function:
protein binding [GO:0005515],
ATP binding [GO:0005524],
nitrate reductase activity [GO:0008940],
molybdopterin cofactor binding [GO:0043546],
metal ion binding [GO:0046872],
molybdopterin adenylyltransferase activity [GO:0061598],
molybdopterin molybdotransferase activity [GO:0061599],
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
receptor binding [GO:0005102],
cytoskeletal protein binding [GO:0008092],
transferase activity [GO:0016740],
identical protein binding [GO:0042802],
binding, bridging [GO:0060090],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
postsynaptic density [GO:0014069],
dendrite [GO:0030425],
postsynaptic membrane [GO:0045211],
postsynaptic specialization [GO:0099572],
postsynaptic specialization membrane [GO:0099634],
intracellular [GO:0005622],
membrane [GO:0016020],
extrinsic component of plasma membrane [GO:0019897],
cell junction [GO:0030054],
extrinsic component of cytoplasmic side of plasma membrane [GO:0031234],
cell projection [GO:0042995],
neuronal cell body [GO:0043025],
synapse [GO:0045202],
inhibitory synapse [GO:0060077],
postsynapse [GO:0098794],
GABA-ergic synapse [GO:0098982],