ANGPTL4
angiopoietin like 4
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
28844647 | BJ, WI-38, IMR-90, MRC-5, HFF, HCA591 | Skin, Lung | Human | YES |
30988157 | IMR-90 | Human | YES | |
31148378 | MRC-5 | Human | YES | |
31534052 | Kidney | Mouse | YES | |
31860636 | 2BS, 293TÂ | Human | YES | |
31945125 | Primary astrocytes derived from brain | Human | YES | |
32029712 | Primary synovial fibroblast | Human | YES | |
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
29321003 | Primary bronchial epithelial cells derived from lung | Human | YES |
GO terms:
Biological Process:
response to hypoxia [GO:0001666],
lipid metabolic process [GO:0006629],
regulation of lipid metabolic process [GO:0019216],
negative regulation of apoptotic process [GO:0043066],
protein unfolding [GO:0043335],
positive regulation of angiogenesis [GO:0045766],
negative regulation of lipoprotein lipase activity [GO:0051005],
triglyceride homeostasis [GO:0070328],
negative regulation of endothelial cell apoptotic process [GO:2000352],
cellular response to starvation [GO:0009267],
positive regulation of lipid metabolic process [GO:0045834],
Molecular Function:
enzyme inhibitor activity [GO:0004857],
receptor binding [GO:0005102],
protein binding [GO:0005515],
identical protein binding [GO:0042802],
Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
blood microparticle [GO:0072562],