ABCD1

ATP binding cassette subfamily D member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

GO terms:

Biological Process:
regulation of oxidative phosphorylation [GO:0002082],
fatty acid beta-oxidation [GO:0006635],
peroxisome organization [GO:0007031],
peroxisomal long-chain fatty acid import [GO:0015910],
fatty-acyl-CoA transport [GO:0015916],
peroxisomal membrane transport [GO:0015919],
fatty acid elongation [GO:0030497],
regulation of fatty acid beta-oxidation [GO:0031998],
positive regulation of fatty acid beta-oxidation [GO:0032000],
fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540],
alpha-linolenic acid metabolic process [GO:0036109],
very long-chain fatty-acyl-CoA catabolic process [GO:0036113],
long-chain fatty acid catabolic process [GO:0042758],
very long-chain fatty acid catabolic process [GO:0042760],
myelin maintenance [GO:0043217],
linoleic acid metabolic process [GO:0043651],
regulation of mitochondrial depolarization [GO:0051900],
transmembrane transport [GO:0055085],
fatty acid homeostasis [GO:0055089],
sterol homeostasis [GO:0055092],
negative regulation of cytokine production involved in inflammatory response [GO:1900016],
regulation of cellular response to oxidative stress [GO:1900407],
negative regulation of reactive oxygen species biosynthetic process [GO:1903427],
neuron projection maintenance [GO:1990535],
positive regulation of unsaturated fatty acid biosynthetic process [GO:2001280],
very long-chain fatty acid metabolic process [GO:0000038],

Molecular Function:
long-chain fatty acid transporter activity [GO:0005324],
protein binding [GO:0005515],
ATP binding [GO:0005524],
fatty-acyl-CoA transporter activity [GO:0015607],
ATPase activity [GO:0016887],
enzyme binding [GO:0019899],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
ADP binding [GO:0043531],
nucleotide binding [GO:0000166],

Cellular Component:
cytoplasm [GO:0005737],
lysosomal membrane [GO:0005765],
peroxisome [GO:0005777],
peroxisomal membrane [GO:0005778],
integral component of peroxisomal membrane [GO:0005779],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
membrane [GO:0016020],
mitochondrial membrane [GO:0031966],
perinuclear region of cytoplasm [GO:0048471],
mitochondrion [GO:0005739],
lysosome [GO:0005764],
endoplasmic reticulum [GO:0005783],
integral component of membrane [GO:0016021],