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ANGPT4

angiopoietin 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
signal transduction [GO:0007165],
Notch signaling pathway [GO:0007219],
endoderm development [GO:0007492],
positive regulation of endothelial cell migration [GO:0010595],
negative regulation of angiogenesis [GO:0016525],
negative regulation of apoptotic process [GO:0043066],
positive regulation of blood vessel endothelial cell migration [GO:0043536],
negative regulation of blood vessel endothelial cell migration [GO:0043537],
positive regulation of angiogenesis [GO:0045766],
Tie signaling pathway [GO:0048014],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
endothelial cell proliferation [GO:0001935],
activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171],
leukocyte migration [GO:0050900],
cellular response to hypoxia [GO:0071456],

Molecular Function:
receptor binding [GO:0005102],
vascular endothelial growth factor receptor binding [GO:0005172],
transmembrane receptor protein tyrosine kinase activator activity [GO:0030297],
receptor tyrosine kinase binding [GO:0030971],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],

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