GMIP

GEM interacting protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA584 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
negative regulation of GTPase activity [GO:0034260],
intracellular signal transduction [GO:0035556],
regulation of small GTPase mediated signal transduction [GO:0051056],
activation of GTPase activity [GO:0090630],
signal transduction [GO:0007165],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
metal ion binding [GO:0046872],

Cellular Component:
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
plasma membrane [GO:0005886],