GLP1R

glucagon like peptide 1 receptor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28963101 Aorta Mouse NO

GO terms:

Biological Process:
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
activation of adenylate cyclase activity [GO:0007190],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
learning or memory [GO:0007611],
regulation of heart contraction [GO:0008016],
cAMP-mediated signaling [GO:0019933],
positive regulation of blood pressure [GO:0045777],
regulation of insulin secretion [GO:0050796],
cellular response to glucagon stimulus [GO:0071377],
response to psychosocial stress [GO:1990911],
signal transduction [GO:0007165],
neuropeptide signaling pathway [GO:0007218],
memory [GO:0007613],
feeding behavior [GO:0007631],
positive regulation of cell proliferation [GO:0008284],
associative learning [GO:0008306],
response to glucose [GO:0009749],
insulin secretion [GO:0030073],
positive regulation of insulin secretion [GO:0032024],
negative regulation of apoptotic process [GO:0043066],
negative regulation of neuron apoptotic process [GO:0043524],
positive regulation of cell differentiation [GO:0045597],
positive regulation of heart contraction [GO:0045823],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
hormone secretion [GO:0046879],
release of sequestered calcium ion into cytosol [GO:0051209],
regulation of calcium ion transport [GO:0051924],

Molecular Function:
transmembrane signaling receptor activity [GO:0004888],
glucagon receptor activity [GO:0004967],
protein binding [GO:0005515],
G-protein coupled peptide receptor activity [GO:0008528],
peptide hormone binding [GO:0017046],
glucagon-like peptide 1 receptor activity [GO:0044508],
peptide receptor activity [GO:0001653],
G-protein coupled receptor activity [GO:0004930],
signaling receptor activity [GO:0038023],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
integral component of membrane [GO:0016021],
membrane [GO:0016020],