ANGEL2

angel homolog 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA231 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of mitotic cell cycle [GO:0045930],
3'-UTR-mediated mRNA stabilization [GO:0070935],
RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503],

Molecular Function:
3'-5'-exoribonuclease activity [GO:0000175],
mRNA 3'-UTR binding [GO:0003730],

Cellular Component:
cytoplasm [GO:0005737],
Cajal body [GO:0015030],