Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31219154 MCF10A Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
ovarian follicle development [GO:0001541],
oocyte maturation [GO:0001556],
response to hypoxia [GO:0001666],
placenta development [GO:0001890],
positive regulation of endothelial cell proliferation [GO:0001938],
diacylglycerol biosynthetic process [GO:0006651],
cell communication [GO:0007154],
activation of phospholipase C activity [GO:0007202],
rRNA transcription [GO:0009303],
response to hormone [GO:0009725],
cell migration [GO:0016477],
negative regulation of translation [GO:0017148],
actin filament polymerization [GO:0030041],
activation of protein kinase B activity [GO:0032148],
activation of phospholipase A2 activity [GO:0032431],
adherens junction organization [GO:0034332],
positive regulation of phosphorylation [GO:0042327],
homeostatic process [GO:0042592],
negative regulation of smooth muscle cell proliferation [GO:0048662],
positive regulation of protein secretion [GO:0050714],
RNA phosphodiester bond hydrolysis [GO:0090501],
response to yeast [GO:0001878],
multicellular organism development [GO:0007275],
central nervous system development [GO:0007417],
antibacterial humoral response [GO:0019731],
antifungal humoral response [GO:0019732],
cell differentiation [GO:0030154],
innate immune response [GO:0045087],
defense response to Gram-positive bacterium [GO:0050830],

Molecular Function:
DNA binding [GO:0003677],
actin binding [GO:0003779],
endonuclease activity [GO:0004519],
ribonuclease activity [GO:0004540],
receptor binding [GO:0005102],
copper ion binding [GO:0005507],
protein binding [GO:0005515],
heparin binding [GO:0008201],
rRNA binding [GO:0019843],
peptide binding [GO:0042277],
protein homodimerization activity [GO:0042803],
nucleic acid binding [GO:0003676],
RNA binding [GO:0003723],
nuclease activity [GO:0004518],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular region [GO:0005576],
basement membrane [GO:0005604],
extracellular space [GO:0005615],
nucleus [GO:0005634],
nucleolus [GO:0005730],
actin cytoskeleton [GO:0015629],
growth cone [GO:0030426],
cytoplasmic vesicle [GO:0031410],
angiogenin-PRI complex [GO:0032311],
neuronal cell body [GO:0043025],