anaphase promoting complex subunit 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell cycle [GO:0007049],
metaphase/anaphase transition of mitotic cell cycle [GO:0007091],
anaphase-promoting complex-dependent catabolic process [GO:0031145],
cell division [GO:0051301],
protein K11-linked ubiquitination [GO:0070979],
ubiquitin-dependent protein catabolic process [GO:0006511],
regulation of mitotic cell cycle phase transition [GO:1901990],

Molecular Function:
protein binding [GO:0005515],
binding, bridging [GO:0060090],

Cellular Component:
nucleus [GO:0005634],
anaphase-promoting complex [GO:0005680],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],