GDI2

GDP dissociation inhibitor 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
signal transduction [GO:0007165],
small GTPase mediated signal transduction [GO:0007264],
protein transport [GO:0015031],
vesicle-mediated transport [GO:0016192],
neutrophil degranulation [GO:0043312],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
RNA binding [GO:0003723],
Rab GDP-dissociation inhibitor activity [GO:0005093],
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rab GTPase binding [GO:0017137],
GDP-dissociation inhibitor activity [GO:0005092],
small GTPase binding [GO:0031267],

Cellular Component:
extracellular region [GO:0005576],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
focal adhesion [GO:0005925],
membrane [GO:0016020],
vesicle [GO:0031982],
secretory granule lumen [GO:0034774],
azurophil granule lumen [GO:0035578],
synapse [GO:0045202],
extracellular exosome [GO:0070062],
myelin sheath [GO:0043209],