GCNT1

glucosaminyl (N-acetyl) transferase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
30987592 MCF7 Breast Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
glycoprotein biosynthetic process [GO:0009101],
O-glycan processing [GO:0016266],
response to insulin [GO:0032868],
tissue morphogenesis [GO:0048729],
leukocyte tethering or rolling [GO:0050901],
cell adhesion molecule production [GO:0060352],
kidney morphogenesis [GO:0060993],

Molecular Function:
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity [GO:0003829],
protein binding [GO:0005515],
acetylglucosaminyltransferase activity [GO:0008375],
transferase activity [GO:0016740],
transferase activity, transferring glycosyl groups [GO:0016757],

Cellular Component:
Golgi membrane [GO:0000139],
extracellular space [GO:0005615],
trans-Golgi network [GO:0005802],
integral component of membrane [GO:0016021],
Golgi cisterna [GO:0031985],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],