AMPD2
adenosine monophosphate deaminase 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
29548335 | Saos-2, Li-Fraumeni | Human | YES |
GO terms:
Biological Process:
IMP biosynthetic process [GO:0006188],
IMP salvage [GO:0032264],
purine-containing compound salvage [GO:0043101],
AMP metabolic process [GO:0046033],
cyclic purine nucleotide metabolic process [GO:0052652],
energy homeostasis [GO:0097009],
nucleotide metabolic process [GO:0009117],
purine ribonucleoside monophosphate biosynthetic process [GO:0009168],
cholesterol homeostasis [GO:0042632],
ATP metabolic process [GO:0046034],
GTP metabolic process [GO:0046039],
glomerular visceral epithelial cell development [GO:0072015],
Molecular Function:
AMP deaminase activity [GO:0003876],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
hydrolase activity [GO:0016787],
deaminase activity [GO:0019239],
Cellular Component:
cytosol [GO:0005829],