GALNS

galactosamine (N-acetyl)-6-sulfatase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
keratan sulfate catabolic process [GO:0042340],
neutrophil degranulation [GO:0043312],

Molecular Function:
N-acetylgalactosamine-4-sulfatase activity [GO:0003943],
arylsulfatase activity [GO:0004065],
sulfuric ester hydrolase activity [GO:0008484],
N-acetylgalactosamine-6-sulfatase activity [GO:0043890],
metal ion binding [GO:0046872],
catalytic activity [GO:0003824],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular region [GO:0005576],
azurophil granule lumen [GO:0035578],
lysosomal lumen [GO:0043202],
extracellular exosome [GO:0070062],
lysosome [GO:0005764],