AMD1

adenosylmethionine decarboxylase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
S-adenosylmethioninamine biosynthetic process [GO:0006557],
polyamine metabolic process [GO:0006595],
spermine biosynthetic process [GO:0006597],
spermidine biosynthetic process [GO:0008295],
S-adenosylmethionine metabolic process [GO:0046500],
in utero embryonic development [GO:0001701],
polyamine biosynthetic process [GO:0006596],

Molecular Function:
adenosylmethionine decarboxylase activity [GO:0004014],
putrescine binding [GO:0019810],
protein binding [GO:0005515],
lyase activity [GO:0016829],
carboxy-lyase activity [GO:0016831],

Cellular Component:
cytosol [GO:0005829],