FZD7
frizzled class receptor 7
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
GO terms:
Biological Process:
regulation of transcription, DNA-templated [GO:0006355],
G-protein coupled receptor signaling pathway [GO:0007186],
negative regulation of cell-substrate adhesion [GO:0010812],
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834],
stem cell population maintenance [GO:0019827],
neuron differentiation [GO:0030182],
T cell differentiation in thymus [GO:0033077],
substrate adhesion-dependent cell spreading [GO:0034446],
non-canonical Wnt signaling pathway [GO:0035567],
non-canonical Wnt signaling pathway via JNK cascade [GO:0038031],
positive regulation of phosphorylation [GO:0042327],
negative regulation of ectodermal cell fate specification [GO:0042666],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of JNK cascade [GO:0046330],
somatic stem cell division [GO:0048103],
positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054],
canonical Wnt signaling pathway [GO:0060070],
Wnt signaling pathway, planar cell polarity pathway [GO:0060071],
mesenchymal to epithelial transition [GO:0060231],
regulation of canonical Wnt signaling pathway [GO:0060828],
cellular response to retinoic acid [GO:0071300],
negative regulation of cardiac muscle cell differentiation [GO:2000726],
signal transduction [GO:0007165],
cell surface receptor signaling pathway [GO:0007166],
multicellular organism development [GO:0007275],
Wnt signaling pathway [GO:0016055],
Molecular Function:
G-protein coupled receptor activity [GO:0004930],
frizzled binding [GO:0005109],
protein binding [GO:0005515],
phosphatidylinositol-4,5-bisphosphate binding [GO:0005546],
Wnt-protein binding [GO:0017147],
PDZ domain binding [GO:0030165],
Wnt-activated receptor activity [GO:0042813],
transmembrane signaling receptor activity [GO:0004888],
Cellular Component:
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
intracellular membrane-bounded organelle [GO:0043231],
recycling endosome membrane [GO:0055038],
endosome [GO:0005768],
membrane [GO:0016020],