ALYREF

Aly/REF export factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of DNA recombination [GO:0000018],
mRNA splicing, via spliceosome [GO:0000398],
osteoblast differentiation [GO:0001649],
RNA export from nucleus [GO:0006405],
mRNA export from nucleus [GO:0006406],
viral process [GO:0016032],
mRNA 3'-end processing [GO:0031124],
replication fork processing [GO:0031297],
positive regulation of DNA-templated transcription, elongation [GO:0032786],
viral mRNA export from host cell nucleus [GO:0046784],
mRNA processing [GO:0006397],
RNA splicing [GO:0008380],
mRNA transport [GO:0051028],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
nucleic acid binding [GO:0003676],
single-stranded DNA binding [GO:0003697],

Cellular Component:
transcription export complex [GO:0000346],
nuclear chromosome, telomeric region [GO:0000784],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
membrane [GO:0016020],
nuclear speck [GO:0016607],
exon-exon junction complex [GO:0035145],
extracellular exosome [GO:0070062],
catalytic step 2 spliceosome [GO:0071013],
spliceosomal complex [GO:0005681],