FZD3

frizzled class receptor 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
establishment of planar polarity [GO:0001736],
neuron migration [GO:0001764],
neural tube closure [GO:0001843],
hair follicle development [GO:0001942],
positive regulation of neuroblast proliferation [GO:0002052],
G-protein coupled receptor signaling pathway [GO:0007186],
Wnt signaling pathway, calcium modulating pathway [GO:0007223],
neuron differentiation [GO:0030182],
cell proliferation in midbrain [GO:0033278],
non-canonical Wnt signaling pathway [GO:0035567],
post-anal tail morphogenesis [GO:0036342],
dopaminergic neuron axon guidance [GO:0036514],
serotonergic neuron axon guidance [GO:0036515],
inner ear morphogenesis [GO:0042472],
response to drug [GO:0042493],
negative regulation of mitotic cell cycle, embryonic [GO:0045976],
response to electrical stimulus [GO:0051602],
canonical Wnt signaling pathway [GO:0060070],
Wnt signaling pathway, planar cell polarity pathway [GO:0060071],
sympathetic ganglion development [GO:0061549],
commissural neuron axon guidance [GO:0071679],
negative regulation of execution phase of apoptosis [GO:1900118],
midbrain morphogenesis [GO:1904693],
planar cell polarity pathway involved in axon guidance [GO:1904938],
signal transduction [GO:0007165],
cell surface receptor signaling pathway [GO:0007166],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
Wnt signaling pathway [GO:0016055],
midbrain development [GO:0030901],

Molecular Function:
G-protein coupled receptor activity [GO:0004930],
protein binding [GO:0005515],
Wnt-protein binding [GO:0017147],
PDZ domain binding [GO:0030165],
Wnt-activated receptor activity [GO:0042813],
transmembrane signaling receptor activity [GO:0004888],

Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
cell surface [GO:0009986],
integral component of membrane [GO:0016021],
apical plasma membrane [GO:0016324],
lateral plasma membrane [GO:0016328],
axon [GO:0030424],
dendrite [GO:0030425],
filopodium tip [GO:0032433],
neuronal cell body [GO:0043025],
presynaptic active zone [GO:0048786],
membrane [GO:0016020],
apical part of cell [GO:0045177],