FZD2

frizzled class receptor 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
membranous septum morphogenesis [GO:0003149],
muscular septum morphogenesis [GO:0003150],
outflow tract morphogenesis [GO:0003151],
G-protein coupled receptor signaling pathway [GO:0007186],
Wnt signaling pathway, calcium modulating pathway [GO:0007223],
sensory perception of smell [GO:0007608],
Wnt signaling pathway [GO:0016055],
neuron differentiation [GO:0030182],
epithelial cell differentiation [GO:0030855],
non-canonical Wnt signaling pathway [GO:0035567],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091],
hard palate development [GO:0060022],
canonical Wnt signaling pathway [GO:0060070],
Wnt signaling pathway, planar cell polarity pathway [GO:0060071],
inner ear receptor cell development [GO:0060119],
cochlea morphogenesis [GO:0090103],
planar cell polarity pathway involved in neural tube closure [GO:0090179],
beta-catenin destruction complex disassembly [GO:1904886],
signal transduction [GO:0007165],
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
cell-cell signaling [GO:0007267],
multicellular organism development [GO:0007275],
ventricular septum morphogenesis [GO:0060412],

Molecular Function:
G-protein coupled receptor activity [GO:0004930],
protein binding [GO:0005515],
Wnt-protein binding [GO:0017147],
PDZ domain binding [GO:0030165],
Wnt-activated receptor activity [GO:0042813],
transmembrane signaling receptor activity [GO:0004888],
identical protein binding [GO:0042802],
protein heterodimerization activity [GO:0046982],

Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
focal adhesion [GO:0005925],
integral component of membrane [GO:0016021],
clathrin-coated endocytic vesicle membrane [GO:0030669],
membrane [GO:0016020],