FMR1 autosomal homolog 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27606879 UMSCC-11A, -11B, -74A and -74B, SCC4, SCC9, SCC25, CAL27 Head-Neck Human NO
29142209 UM-SCC-74B Tongue Human NO

GO terms:

Biological Process:
regulation of alternative mRNA splicing, via spliceosome [GO:0000381],
positive regulation of protein phosphorylation [GO:0001934],
apoptotic process [GO:0006915],
muscle organ development [GO:0007517],
negative regulation of translation [GO:0017148],
cell differentiation [GO:0030154],
regulation of mRNA stability [GO:0043488],
positive regulation of translation [GO:0045727],
regulation of filopodium assembly [GO:0051489],
positive regulation of gene silencing by miRNA [GO:2000637],
positive regulation of response to DNA damage stimulus [GO:2001022],
regulation of translation [GO:0006417],
multicellular organism development [GO:0007275],

Molecular Function:
RNA binding [GO:0003723],
mRNA binding [GO:0003729],
mRNA 3'-UTR binding [GO:0003730],
protein binding [GO:0005515],
RNA strand annealing activity [GO:0033592],
protein homodimerization activity [GO:0042803],
translation regulator activity [GO:0045182],
protein heterodimerization activity [GO:0046982],
G-quadruplex RNA binding [GO:0002151],
nucleic acid binding [GO:0003676],

Cellular Component:
nucleus [GO:0005634],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
polysome [GO:0005844],
postsynaptic density [GO:0014069],
membrane [GO:0016020],
axon [GO:0030424],
growth cone [GO:0030426],
ribonucleoprotein granule [GO:0035770],
cytoplasmic ribonucleoprotein granule [GO:0036464],
neuronal cell body [GO:0043025],
costamere [GO:0043034],
dendritic spine [GO:0043197],
dendritic spine neck [GO:0044326],
perinuclear region of cytoplasm [GO:0048471],
presynapse [GO:0098793],
glutamatergic synapse [GO:0098978],
dendritic filopodium [GO:1902737],
dendrite [GO:0030425],
postsynapse [GO:0098794],