ALS2 C-terminal like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
endosome organization [GO:0007032],
protein localization [GO:0008104],
positive regulation of GTPase activity [GO:0043547],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rab guanyl-nucleotide exchange factor activity [GO:0017112],
Rab GTPase binding [GO:0017137],
identical protein binding [GO:0042802],

Cellular Component:
cytoplasm [GO:0005737],
cytoplasmic vesicle [GO:0031410],
cytosol [GO:0005829],