FRMD7

FERM domain containing 7

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
positive regulation of lamellipodium assembly [GO:0010592],
regulation of neuron projection development [GO:0010975],
negative regulation of protein binding [GO:0032091],
positive regulation of small GTPase mediated signal transduction [GO:0051057],
negative regulation of stress fiber assembly [GO:0051497],
nervous system development [GO:0007399],

Molecular Function:
molecular_function [GO:0003674],
Rac guanyl-nucleotide exchange factor activity [GO:0030676],
protein binding [GO:0005515],

Cellular Component:
extracellular space [GO:0005615],
cytoskeleton [GO:0005856],
growth cone [GO:0030426],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],
cell projection [GO:0042995],