ALPL

alkaline phosphatase, biomineralization associated

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated
Pubmed ID	Cell line	Tissue	Source	High-throughput
29548335	Saos-2, Li-Fraumeni		Human	YES
31882658	Primary mesenchymal stells derived from bone marrow		Human	NO
32473528	Primary follicle cells derived from tooth		Human	NO

GO terms:

Biological Process:
skeletal system development [GO:0001501],
osteoblast differentiation [GO:0001649],
endochondral ossification [GO:0001958],
developmental process involved in reproduction [GO:0003006],
dephosphorylation [GO:0016311],
response to lipopolysaccharide [GO:0032496],
response to vitamin D [GO:0033280],
response to antibiotic [GO:0046677],
response to glucocorticoid [GO:0051384],
cellular response to organic cyclic compound [GO:0071407],
cementum mineralization [GO:0071529],

Molecular Function:
alkaline phosphatase activity [GO:0004035],
protein binding [GO:0005515],
pyrophosphatase activity [GO:0016462],
metal ion binding [GO:0046872],
catalytic activity [GO:0003824],
hydrolase activity [GO:0016787],
phosphatase activity [GO:0016791],

Cellular Component:
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
membrane [GO:0016020],
extracellular matrix [GO:0031012],
anchored component of membrane [GO:0031225],
extracellular membrane-bounded organelle [GO:0065010],
extracellular exosome [GO:0070062],
extracellular space [GO:0005615],