FOXP2

forkhead box P2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
positive regulation of mesenchymal cell proliferation [GO:0002053],
skeletal muscle tissue development [GO:0007519],
post-embryonic development [GO:0009791],
cerebellum development [GO:0021549],
caudate nucleus development [GO:0021757],
putamen development [GO:0021758],
cerebral cortex development [GO:0021987],
response to testosterone [GO:0033574],
vocal learning [GO:0042297],
camera-type eye development [GO:0043010],
negative regulation of transcription, DNA-templated [GO:0045892],
lung alveolus development [GO:0048286],
smooth muscle tissue development [GO:0048745],
righting reflex [GO:0060013],
positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501],
innate vocalization behavior [GO:0098582],
regulation of transcription, DNA-templated [GO:0006355],
embryo development [GO:0009790],
lung development [GO:0030324],
growth [GO:0040007],
positive regulation of epithelial cell proliferation [GO:0050679],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001227],
DNA binding [GO:0003677],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
sequence-specific DNA binding [GO:0043565],
metal ion binding [GO:0046872],
androgen receptor binding [GO:0050681],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],