FOXP1

forkhead box P1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
33252174 SF-MSCs, BMSCs Human NO
33252174 SF-MSCs, BMSCs mouse NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28240601 MSCs, hMPC Human NO
31983656 MSC Human YES
33296652 heart heart Human NO

GO terms:

Biological Process:
negative regulation of B cell apoptotic process [GO:0002903],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
cellular response to DNA damage stimulus [GO:0006974],
regulation of gene expression [GO:0010468],
positive regulation of endothelial cell migration [GO:0010595],
negative regulation of gene expression [GO:0010629],
osteoclast differentiation [GO:0030316],
response to lipopolysaccharide [GO:0032496],
interleukin-21 production [GO:0032625],
regulation of tumor necrosis factor production [GO:0032680],
somatic stem cell population maintenance [GO:0035019],
osteoclast development [GO:0036035],
macrophage activation [GO:0042116],
monocyte activation [GO:0042117],
endothelial cell activation [GO:0042118],
regulation of monocyte differentiation [GO:0045655],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of smooth muscle cell proliferation [GO:0048661],
regulation of interleukin-1 beta secretion [GO:0050706],
regulation of inflammatory response [GO:0050727],
positive regulation of B cell receptor signaling pathway [GO:0050861],
negative regulation of androgen receptor signaling pathway [GO:0060766],
T follicular helper cell differentiation [GO:0061470],
regulation of defense response to bacterium [GO:1900424],
regulation of macrophage colony-stimulating factor production [GO:1901256],
regulation of endothelial tube morphogenesis [GO:1901509],
regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000341],
regulation of interleukin-12 secretion [GO:2001182],
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
in utero embryonic development [GO:0001701],
positive regulation of mesenchymal cell proliferation [GO:0002053],
pre-B cell differentiation [GO:0002329],
positive regulation of immunoglobulin production [GO:0002639],
regulation of transcription, DNA-templated [GO:0006355],
heart development [GO:0007507],
skeletal muscle tissue development [GO:0007519],
motor neuron axon guidance [GO:0008045],
embryo development [GO:0009790],
ventral spinal cord development [GO:0021517],
lung development [GO:0030324],
immunoglobulin V(D)J recombination [GO:0033152],
sarcomere organization [GO:0045214],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
smooth muscle tissue development [GO:0048745],
positive regulation of epithelial cell proliferation [GO:0050679],
cardiac muscle cell differentiation [GO:0055007],
regulation of cardiac muscle cell proliferation [GO:0060043],
negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052],
lung secretory cell differentiation [GO:0061140],
cardiovascular system development [GO:0072358],
innate vocalization behavior [GO:0098582],
regulation of action potential [GO:0098900],
regulation of lung goblet cell differentiation [GO:1901249],
negative regulation of lung goblet cell differentiation [GO:1901250],
cellular response to ionomycin [GO:1904637],
positive regulation of hydrogen peroxide-induced cell death [GO:1905206],

Molecular Function:
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
core promoter sequence-specific DNA binding [GO:0001046],
protein binding [GO:0005515],
identical protein binding [GO:0042802],
protein self-association [GO:0043621],
metal ion binding [GO:0046872],
androgen receptor binding [GO:0050681],
transcription regulatory region sequence-specific DNA binding [GO:0000976],
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001227],
DNA binding [GO:0003677],
chromatin binding [GO:0003682],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
transcription factor binding [GO:0008134],
sequence-specific DNA binding [GO:0043565],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],