FOXM1

forkhead box M1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
25477198 Liver Mouse NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
18408007 NIH/3T3 Mouse NO
23262037 Hep 3B2.1-7, Hep G2, MHCC-97-H, MHCC-97-L Human NO
23804320 NIH/3T3 Mouse NO
24141789 MCF-7, MDA-MB-231, ZR-75-1, MEF, 48BR, NBS1-LBI Human, mouse NO
25071344  GBC-SD Human NO
25355277 Primary mesenchymal stem cells derived from bone marrow Human NO
25661872 Liver Mouse NO
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
27385468 Primary keratinocytes derived from skin Human NO
29050219 MCF7 Human NO
29321003 Primary bronchial epithelial cells derived from lung Human YES
29449545 HMEC, MRC-5, IMR-90, 293GP, WI-38, HUVEC Human NO
29548335 Li Fraumeni Human YES
30026603 HDF, primary fibroblasts derived from ear Human, Mouse NO
30920150 Primary vascular progenitor cells derived from artery Human YES
30987592 MCF7 Breast Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
32100207 HFL-1 Human NO

GO terms:

Biological Process:
G2/M transition of mitotic cell cycle [GO:0000086],
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
vasculogenesis [GO:0001570],
DNA repair [GO:0006281],
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978],
positive regulation of cell proliferation [GO:0008284],
negative regulation of stress-activated MAPK cascade [GO:0032873],
regulation of cell proliferation [GO:0042127],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
regulation of Ras protein signal transduction [GO:0046578],
regulation of cell cycle [GO:0051726],
regulation of cell cycle arrest [GO:0071156],
negative regulation of cell aging [GO:0090344],
regulation of reactive oxygen species metabolic process [GO:2000377],
positive regulation of double-strand break repair [GO:2000781],
liver development [GO:0001889],
regulation of transcription, DNA-templated [GO:0006355],
cellular response to DNA damage stimulus [GO:0006974],
cell cycle [GO:0007049],

Molecular Function:
RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],
protein kinase binding [GO:0019901],
transcription regulatory region sequence-specific DNA binding [GO:0000976],
DNA binding [GO:0003677],
sequence-specific DNA binding [GO:0043565],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],