FLNC

filamin C

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31148378 MRC-5 Human YES
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell junction assembly [GO:0034329],
muscle fiber development [GO:0048747],
actin filament-based process [GO:0030029],

Molecular Function:
actin binding [GO:0003779],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
ankyrin binding [GO:0030506],
identical protein binding [GO:0042802],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
focal adhesion [GO:0005925],
sarcoplasm [GO:0016528],
Z disc [GO:0030018],
sarcolemma [GO:0042383],
costamere [GO:0043034],
actin cytoskeleton [GO:0015629],
membrane [GO:0016020],