ALMS1 centrosome and basal body associated protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
G2/M transition of mitotic cell cycle [GO:0000086],
regulation of G2/M transition of mitotic cell cycle [GO:0010389],
endosomal transport [GO:0016197],
regulation of centriole replication [GO:0046599],
regulation of stress fiber assembly [GO:0051492],
ciliary basal body docking [GO:0097711],
cellular glucose homeostasis [GO:0001678],
establishment of planar polarity [GO:0001736],
lipid metabolic process [GO:0006629],
spermatid development [GO:0007286],
sensory perception of sound [GO:0007605],
calcium-mediated signaling [GO:0019722],
ovulation [GO:0030728],
negative regulation of multicellular organism growth [GO:0040015],
glucose homeostasis [GO:0042593],
cholesterol homeostasis [GO:0042632],
negative regulation of apoptotic process [GO:0043066],
regulation of fat cell differentiation [GO:0045598],
retinal rod cell development [GO:0046548],
epithelial cell proliferation [GO:0050673],
inner ear receptor stereocilium organization [GO:0060122],
cilium assembly [GO:0060271],

Molecular Function:
molecular_function [GO:0003674],
protein binding [GO:0005515],
microtubule binding [GO:0008017],
alpha-actinin binding [GO:0051393],

Cellular Component:
spindle pole [GO:0000922],
centrosome [GO:0005813],
centriole [GO:0005814],
cytosol [GO:0005829],
cilium [GO:0005929],
ciliary basal body [GO:0036064],