fibroblast growth factor 18

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
MAPK cascade [GO:0000165],
angiogenesis [GO:0001525],
regulation of endothelial cell proliferation [GO:0001936],
intramembranous ossification [GO:0001957],
endochondral ossification [GO:0001958],
chondrocyte development [GO:0002063],
signal transduction [GO:0007165],
cell-cell signaling [GO:0007267],
positive regulation of cell proliferation [GO:0008284],
fibroblast growth factor receptor signaling pathway [GO:0008543],
anatomical structure morphogenesis [GO:0009653],
lung development [GO:0030324],
positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949],
positive regulation of chondrocyte differentiation [GO:0032332],
positive regulation of MAP kinase activity [GO:0043406],
positive regulation of blood vessel endothelial cell migration [GO:0043536],
positive regulation of angiogenesis [GO:0045766],
positive regulation of protein kinase B signaling [GO:0051897],
positive regulation of ERK1 and ERK2 cascade [GO:0070374],
regulation of sprouting angiogenesis [GO:1903670],
positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546],
ossification [GO:0001503],
nervous system development [GO:0007399],
positive regulation of hepatocyte proliferation [GO:2000347],

Molecular Function:
type 1 fibroblast growth factor receptor binding [GO:0005105],
type 2 fibroblast growth factor receptor binding [GO:0005111],
growth factor activity [GO:0008083],
fibroblast growth factor receptor binding [GO:0005104],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleolus [GO:0005730],
nucleus [GO:0005634],
cytoplasm [GO:0005737],