FGF10

fibroblast growth factor 10

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
establishment of mitotic spindle orientation [GO:0000132],
MAPK cascade [GO:0000165],
activation of MAPK activity [GO:0000187],
angiogenesis [GO:0001525],
metanephros development [GO:0001656],
organ induction [GO:0001759],
mesonephros development [GO:0001823],
blood vessel remodeling [GO:0001974],
metanephros morphogenesis [GO:0003338],
determination of left/right symmetry [GO:0007368],
salivary gland development [GO:0007431],
negative regulation of cell proliferation [GO:0008285],
fibroblast growth factor receptor signaling pathway [GO:0008543],
regulation of smoothened signaling pathway [GO:0008589],
embryonic pattern specification [GO:0009880],
positive regulation of epithelial cell migration [GO:0010634],
positive regulation of keratinocyte proliferation [GO:0010838],
pituitary gland development [GO:0021983],
embryonic genitalia morphogenesis [GO:0030538],
thyroid gland development [GO:0030878],
otic vesicle formation [GO:0030916],
positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949],
pancreas development [GO:0031016],
hair follicle morphogenesis [GO:0031069],
embryonic camera-type eye development [GO:0031076],
actin cytoskeleton reorganization [GO:0031532],
response to estradiol [GO:0032355],
response to lipopolysaccharide [GO:0032496],
positive regulation of ATPase activity [GO:0032781],
lacrimal gland development [GO:0032808],
regulation of activin receptor signaling pathway [GO:0032925],
protein localization to cell surface [GO:0034394],
somatic stem cell population maintenance [GO:0035019],
wound healing [GO:0042060],
tissue regeneration [GO:0042246],
odontogenesis of dentin-containing tooth [GO:0042475],
muscle cell fate commitment [GO:0042693],
positive regulation of MAPK cascade [GO:0043410],
negative regulation of cell differentiation [GO:0045596],
positive regulation of DNA repair [GO:0045739],
positive regulation of Notch signaling pathway [GO:0045747],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of Ras protein signal transduction [GO:0046579],
regulation of saliva secretion [GO:0046877],
positive regulation of fibroblast proliferation [GO:0048146],
spleen development [GO:0048536],
thymus development [GO:0048538],
embryonic digestive tract morphogenesis [GO:0048557],
branching morphogenesis of an epithelial tube [GO:0048754],
female genitalia morphogenesis [GO:0048807],
male genitalia morphogenesis [GO:0048808],
positive regulation of lymphocyte proliferation [GO:0050671],
epithelial cell proliferation [GO:0050673],
urothelial cell proliferation [GO:0050674],
positive regulation of urothelial cell proliferation [GO:0050677],
positive regulation of epithelial cell proliferation [GO:0050679],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
white fat cell differentiation [GO:0050872],
positive chemotaxis [GO:0050918],
induction of positive chemotaxis [GO:0050930],
smooth muscle cell differentiation [GO:0051145],
positive regulation of keratinocyte migration [GO:0051549],
positive regulation of protein kinase B signaling [GO:0051897],
radial glial cell differentiation [GO:0060019],
positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054],
limb bud formation [GO:0060174],
lung epithelium development [GO:0060428],
lung saccule development [GO:0060430],
bronchiole morphogenesis [GO:0060436],
bud outgrowth involved in lung branching [GO:0060447],
bud elongation involved in lung branching [GO:0060449],
mesenchymal-epithelial cell signaling involved in lung development [GO:0060496],
Type II pneumocyte differentiation [GO:0060510],
prostatic bud formation [GO:0060513],
fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595],
mammary gland bud formation [GO:0060615],
submandibular salivary gland formation [GO:0060661],
epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664],
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665],
branch elongation involved in salivary gland morphogenesis [GO:0060667],
semicircular canal fusion [GO:0060879],
mesenchymal cell differentiation involved in lung development [GO:0060915],
secretion by lung epithelial cell involved in lung growth [GO:0061033],
lung proximal/distal axis specification [GO:0061115],
tear secretion [GO:0070075],
positive regulation of white fat cell proliferation [GO:0070352],
ERK1 and ERK2 cascade [GO:0070371],
positive regulation of ERK1 and ERK2 cascade [GO:0070374],
Harderian gland development [GO:0070384],
negative regulation of cell cycle arrest [GO:0071157],
positive regulation of hair follicle cell proliferation [GO:0071338],
positive regulation of canonical Wnt signaling pathway [GO:0090263],
positive regulation of G1/S transition of mitotic cell cycle [GO:1900087],
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240],
chemotaxis [GO:0006935],
cell-cell signaling [GO:0007267],
salivary gland morphogenesis [GO:0007435],
positive regulation of cell proliferation [GO:0008284],
epidermis development [GO:0008544],
animal organ morphogenesis [GO:0009887],
regulation of gene expression [GO:0010468],
positive regulation of Wnt signaling pathway [GO:0030177],
lung development [GO:0030324],
epithelial cell differentiation [GO:0030855],
limb morphogenesis [GO:0035108],
organ growth [GO:0035265],
inner ear morphogenesis [GO:0042472],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of mitotic cell cycle [GO:0045931],
lung alveolus development [GO:0048286],
blood vessel morphogenesis [GO:0048514],
digestive tract development [GO:0048565],
embryonic digestive tract development [GO:0048566],
animal organ formation [GO:0048645],
epidermis morphogenesis [GO:0048730],
semicircular canal morphogenesis [GO:0048752],
limb development [GO:0060173],
lung morphogenesis [GO:0060425],
epithelial tube branching involved in lung morphogenesis [GO:0060441],
branching involved in salivary gland morphogenesis [GO:0060445],
respiratory system development [GO:0060541],
mammary gland specification [GO:0060594],

Molecular Function:
fibroblast growth factor receptor binding [GO:0005104],
type 2 fibroblast growth factor receptor binding [GO:0005111],
protein binding [GO:0005515],
growth factor activity [GO:0008083],
heparin binding [GO:0008201],
chemoattractant activity [GO:0042056],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleus [GO:0005634],
plasma membrane [GO:0005886],
cell surface [GO:0009986],