ATP binding cassette subfamily C member 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30977188 MSC Human YES
30987592 MCF7 Breast Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

GO terms:

Biological Process:
bile acid and bile salt transport [GO:0015721],
canalicular bile acid transport [GO:0015722],
xenobiotic transport [GO:0042908],
transmembrane transport [GO:0055085],
anion transmembrane transport [GO:0098656],

Molecular Function:
ATP binding [GO:0005524],
bile acid-exporting ATPase activity [GO:0015432],
ATPase activity [GO:0016887],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
xenobiotic transporter activity [GO:0042910],
nucleotide binding [GO:0000166],
transmembrane transporter activity [GO:0022857],

Cellular Component:
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
integral component of plasma membrane [GO:0005887],
basolateral plasma membrane [GO:0016323],