FCHO1

FCH and mu domain containing endocytic adaptor 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
clathrin coat assembly [GO:0048268],
membrane organization [GO:0061024],
clathrin-dependent endocytosis [GO:0072583],
endocytosis [GO:0006897],

Molecular Function:
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
AP-2 adaptor complex binding [GO:0035612],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
clathrin-coated pit [GO:0005905],
clathrin-coated vesicle [GO:0030136],
membrane [GO:0016020],