FARSB

phenylalanyl-tRNA synthetase subunit beta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
translation [GO:0006412],
tRNA aminoacylation for protein translation [GO:0006418],
phenylalanyl-tRNA aminoacylation [GO:0006432],
protein heterotetramerization [GO:0051290],

Molecular Function:
magnesium ion binding [GO:0000287],
RNA binding [GO:0003723],
phenylalanine-tRNA ligase activity [GO:0004826],
protein binding [GO:0005515],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
aminoacyl-tRNA ligase activity [GO:0004812],
ligase activity [GO:0016874],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
phenylalanine-tRNA ligase complex [GO:0009328],
membrane [GO:0016020],