ALDOC

aldolase, fructose-bisphosphate C

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
fructose metabolic process [GO:0006000],
gluconeogenesis [GO:0006094],
glycolytic process [GO:0006096],
fructose 1,6-bisphosphate metabolic process [GO:0030388],
epithelial cell differentiation [GO:0030855],
neutrophil degranulation [GO:0043312],
canonical glycolysis [GO:0061621],
apoptotic process [GO:0006915],
aging [GO:0007568],

Molecular Function:
fructose-bisphosphate aldolase activity [GO:0004332],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
catalytic activity [GO:0003824],
lyase activity [GO:0016829],
identical protein binding [GO:0042802],
macromolecular complex binding [GO:0044877],

Cellular Component:
extracellular region [GO:0005576],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
secretory granule lumen [GO:0034774],
extracellular exosome [GO:0070062],
tertiary granule lumen [GO:1904724],
ficolin-1-rich granule lumen [GO:1904813],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
axon [GO:0030424],
postsynaptic cytosol [GO:0099524],