aldolase, fructose-bisphosphate A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31971661 Primary mesenchymal stem cells derived from adipose tissue Mouse YES

GO terms:

Biological Process:
platelet degranulation [GO:0002576],
fructose metabolic process [GO:0006000],
gluconeogenesis [GO:0006094],
glycolytic process [GO:0006096],
ATP biosynthetic process [GO:0006754],
striated muscle contraction [GO:0006941],
actin filament organization [GO:0007015],
binding of sperm to zona pellucida [GO:0007339],
regulation of cell shape [GO:0008360],
fructose 1,6-bisphosphate metabolic process [GO:0030388],
neutrophil degranulation [GO:0043312],
muscle cell cellular homeostasis [GO:0046716],
protein homotetramerization [GO:0051289],
canonical glycolysis [GO:0061621],
methylglyoxal biosynthetic process [GO:0019242],
positive regulation of cell migration [GO:0030335],
glycolytic process through fructose-6-phosphate [GO:0061615],

Molecular Function:
RNA binding [GO:0003723],
actin binding [GO:0003779],
fructose-bisphosphate aldolase activity [GO:0004332],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
tubulin binding [GO:0015631],
identical protein binding [GO:0042802],
cadherin binding [GO:0045296],
fructose binding [GO:0070061],
protease binding [GO:0002020],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleus [GO:0005634],
cytosol [GO:0005829],
actin cytoskeleton [GO:0015629],
membrane [GO:0016020],
platelet alpha granule lumen [GO:0031093],
M band [GO:0031430],
I band [GO:0031674],
secretory granule lumen [GO:0034774],
extracellular exosome [GO:0070062],
tertiary granule lumen [GO:1904724],
ficolin-1-rich granule lumen [GO:1904813],
nuclear heterochromatin [GO:0005720],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
plasma membrane [GO:0005886],
Z disc [GO:0030018],
macromolecular complex [GO:0032991],
sperm fibrous sheath [GO:0035686],
myelin sheath [GO:0043209],