ALDH1L2
aldehyde dehydrogenase 1 family member L2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 25799988 | IMR-90, U2OS | Human | NO | |
| 31945054 | IMR-90 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 30626320 | HBEC | Human | NO | |
GO terms:
Biological Process:
one-carbon metabolic process [GO:0006730],
biosynthetic process [GO:0009058],
10-formyltetrahydrofolate catabolic process [GO:0009258],
folic acid metabolic process [GO:0046655],
oxidation-reduction process [GO:0055114],
Molecular Function:
aldehyde dehydrogenase (NAD) activity [GO:0004029],
formyltetrahydrofolate dehydrogenase activity [GO:0016155],
hydroxymethyl-, formyl- and related transferase activity [GO:0016742],
catalytic activity [GO:0003824],
oxidoreductase activity [GO:0016491],
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620],
Cellular Component:
nucleoplasm [GO:0005654],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],