ATP binding cassette subfamily C member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
leukotriene metabolic process [GO:0006691],
cobalamin metabolic process [GO:0009235],
cobalamin transport [GO:0015889],
glutathione transmembrane transport [GO:0034775],
response to drug [GO:0042493],
xenobiotic transport [GO:0042908],
phospholipid translocation [GO:0045332],
positive regulation of inflammatory response [GO:0050729],
transmembrane transport [GO:0055085],
cell chemotaxis [GO:0060326],
transepithelial transport [GO:0070633],
leukotriene transport [GO:0071716],
sphingolipid translocation [GO:0099039],
cellular response to beta-amyloid [GO:1904646],
response to oxidative stress [GO:0006979],
plasma membrane long-chain fatty acid transport [GO:0015911],
positive regulation of cell migration [GO:0030335],
phospholipid efflux [GO:0033700],
negative regulation of cell death [GO:0060548],
negative regulation of neuron death [GO:1901215],
drug transmembrane export [GO:1990961],

Molecular Function:
ATP binding [GO:0005524],
xenobiotic-transporting ATPase activity [GO:0008559],
cobalamin-transporting ATPase activity [GO:0015420],
glutathione S-conjugate-exporting ATPase activity [GO:0015431],
efflux transmembrane transporter activity [GO:0015562],
ATPase activity [GO:0016887],
lipid-transporting ATPase activity [GO:0034040],
glutathione transmembrane transporter activity [GO:0034634],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
xenobiotic transporter activity [GO:0042910],
nucleotide binding [GO:0000166],
long-chain fatty acid transporter activity [GO:0005324],
hydrolase activity [GO:0016787],
transmembrane transporter activity [GO:0022857],
amide transmembrane transporter activity [GO:0042887],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
basal plasma membrane [GO:0009925],
membrane [GO:0016020],
basolateral plasma membrane [GO:0016323],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
integral component of membrane [GO:0016021],