exocyst complex component 8

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA144 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
exocytosis [GO:0006887],
Golgi to plasma membrane transport [GO:0006893],
endosome organization [GO:0007032],
protein localization [GO:0008104],
protein transport [GO:0015031],
extracellular matrix disassembly [GO:0022617],
cellular protein localization [GO:0034613],
regulation of macroautophagy [GO:0016241],

Molecular Function:
Ral GTPase binding [GO:0017160],
phosphatidylinositol binding [GO:0035091],
protein binding [GO:0005515],

Cellular Component:
exocyst [GO:0000145],
cytoplasm [GO:0005737],
late endosome [GO:0005770],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
cell leading edge [GO:0031252],
cell projection [GO:0042995],
membrane [GO:0016020],
growth cone [GO:0030426],
perinuclear region of cytoplasm [GO:0048471],