activated leukocyte cell adhesion molecule

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31983656 MSC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30854802 Primary progenitor cells derived from heart Human NO

GO terms:

Biological Process:
adaptive immune response [GO:0002250],
cell adhesion [GO:0007155],
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157],
signal transduction [GO:0007165],
motor neuron axon guidance [GO:0008045],
retinal ganglion cell axon guidance [GO:0031290],
axon extension involved in axon guidance [GO:0048846],
neuron projection extension [GO:1990138],
immune system process [GO:0002376],
axon guidance [GO:0007411],

Molecular Function:
receptor binding [GO:0005102],
protein binding [GO:0005515],
identical protein binding [GO:0042802],

Cellular Component:
immunological synapse [GO:0001772],
integral component of plasma membrane [GO:0005887],
focal adhesion [GO:0005925],
external side of plasma membrane [GO:0009897],
axon [GO:0030424],
dendrite [GO:0030425],
intrinsic component of plasma membrane [GO:0031226],
T cell receptor complex [GO:0042101],
neuronal cell body [GO:0043025],
extracellular exosome [GO:0070062],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
cell projection [GO:0042995],