ERCC excision repair 6 like 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA42 Skin, Lung Human YES

GO terms:

Biological Process:
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],
cellular response to reactive oxygen species [GO:0034614],
interstrand cross-link repair [GO:0036297],

Molecular Function:
nucleotide binding [GO:0000166],
DNA binding [GO:0003677],
helicase activity [GO:0004386],
ATP binding [GO:0005524],
hydrolase activity [GO:0016787],
protein kinase binding [GO:0019901],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
centrosome [GO:0005813],
cytoskeleton [GO:0005856],
macromolecular complex [GO:0032991],