AKT interacting protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27512140 Primary fibroblasts derived from foreskin Human NO
30546381 Brain Mouse NO

GO terms:

Biological Process:
protein polyubiquitination [GO:0000209],
positive regulation of protein phosphorylation [GO:0001934],
apoptotic process [GO:0006915],
cellular response to DNA damage stimulus [GO:0006974],
endosome organization [GO:0007032],
lysosome organization [GO:0007040],
endosome to lysosome transport [GO:0008333],
protein transport [GO:0015031],
positive regulation of protein binding [GO:0032092],
early endosome to late endosome transport [GO:0045022],

Molecular Function:
ubiquitin conjugating enzyme activity [GO:0061631],
protein binding [GO:0005515],
ubiquitin-like protein transferase activity [GO:0019787],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
membrane [GO:0016020],
HOPS complex [GO:0030897],
FHF complex [GO:0070695],
cytosol [GO:0005829],