AKT3
AKT serine/threonine kinase 3
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
25323119 | EPCs | Human | NO |
GO terms:
Biological Process:
mitochondrial genome maintenance [GO:0000002],
positive regulation of endothelial cell proliferation [GO:0001938],
protein phosphorylation [GO:0006468],
signal transduction [GO:0007165],
peptidyl-serine phosphorylation [GO:0018105],
intracellular signal transduction [GO:0035556],
positive regulation of blood vessel endothelial cell migration [GO:0043536],
positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050],
positive regulation of vascular endothelial cell proliferation [GO:1905564],
negative regulation of cellular senescence [GO:2000773],
positive regulation of sodium ion transport [GO:0010765],
phosphorylation [GO:0016310],
peptidyl-threonine phosphorylation [GO:0018107],
positive regulation of TOR signaling [GO:0032008],
cellular response to insulin stimulus [GO:0032869],
positive regulation of angiogenesis [GO:0045766],
positive regulation of cell size [GO:0045793],
brain morphogenesis [GO:0048854],
homeostasis of number of cells within a tissue [GO:0048873],
Molecular Function:
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
protein kinase C binding [GO:0005080],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
membrane [GO:0016020],
plasma membrane [GO:0005886],